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 Expert  107807

Expert in Membrane Traffic

Available for your Consulting and Expert Witness Needs

Texas (TX)
Education Work History Career AccomplishmentsPublicationsConsulting Services Expert Witness

Summary of Expertise:

Listed with other top experts in: 

MEMBRANE TRAFFIC. All of Expert's work in the last ten years has involved membrane traffic, ranging from genetic analysis of endocytosis and secretion in mammalian cells to biochemical analysis of the entry of protein toxins, including immunotoxins, into cells.

HYBRID TOXINS; IMMUNOTOXINS. The goal of Expert's work with protein toxins is the construction of more potent and specific hybrid immunotoxins that may have chemotherapeutic value. He and his colleagues have applied to patent an approach in this area using toxins based on Pseudomonas aeruginosa exotoxin A.

ENDOCYTOSIS. Expert has done extensive work on the endocytosis of protein toxins and on the endocytosis of transferrin and the transferrin receptor. He has also worked a great deal on mammalian cells expressing genetic defects in the endocytic pathway.

SECRETION. Over the last four years, Expert has studied secretion as it relates to mutants he has isolated that are defective in the secretory pathway.

PSEUDOMONAS AERUGINOSA EXOTOXIN A. For the last five years, Expert has been studying the molecular and cellular biology of the Pseudomonas aeruginosa extoxin A, especially ways to improve immunotoxins made with exotoxin A. He and his colleagues submitted a patent application covering some of this work.

DIPHTHERIA TOXIN. Although the diphtheria toxin is not currently his focus, Expert has had a lot of experience with this toxin in the past and continues to follow the literature in the field.


cancer chemotherapeutic agent


cell anatomy


cell culture


cell membrane transport


cell physiology


cell surface interaction






hybrid toxin






receptor-mediated endocytosis

Show Secondary and Basic Areas of Expertise
Expert may consult nationally and internationally, and is also local to the following cities: Dallas, Texas;  Fort Worth, Texas;  Arlington, Texas;  Plano, Texas;  Garland, Texas;  Irving, Texas;  Grand Prairie, Texas;  Mesquite, Texas;  Waco, Texas;  and Carrollton, Texas.

Year   Degree   Subject   Institution  
1974   PhD   Biological Chemistry   UCLA  
1968   BA   Chemistry   University of Washington - Seattle  

Work History:
Years   Employer   Title  

1980 to 2000






1974 to 1980



Various postdoctoral fellowships


Career Accomplishments:

Expert is a member of the American Society of Cell Biology and the American Association for the Advancement of Science.

Publications and Patents Summary

Expert has over thirty published research articles and reviews in his fields of expertise.

Selected Publications and Publishers  
 - Elsevier  
 - Marcel Dekker  
 - Journal of Cell Biology  
 - Journal of Biological Chemistry  

Consulting Services:
Click the green button above to contact Expert for a free initial screening call regarding your expert consulting needs.  Expert is available for consulting to corporate, legal and government clients.  Remember, your initial screening call to speak with Expert is free.

Expert Witness:
Click the green button above to contact Expert for a free initial screening call regarding expert testimony, litigation consulting and support, forensic services, or any related expert witness services.  A few litigation needs include product liability, personal injury, economic loss, intellectual property (patent, trademark, trade secret, copyright), and insurance matters.  Remember, your initial screening call to speak with Expert is free.


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