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 Expert  717764

Expert in Biomolecular Research Resource

Available for your Consulting and Expert Witness Needs

California (CA)
Education Work History Career AccomplishmentsPublicationsConsulting Services Expert Witness

Summary of Expertise:

Listed with other top experts in: 

AMINO ACIDS; PEPTIDES; PROTEINS; PROTEIN PURIFICATION. Expert has devoted a considerable portion of his career to providing the capability to purify, sequence, and synthesize proteins. He has helped develop the technologies and protocols needed as well as implement the ideas provided by others. While samples and sequences from many investigators and sources have been successfully completed, Expert has emphasized techniques to sequence rare, difficult to purify, and otherwise difficult to sequence proteins and peptides.

PROTEIN STRUCTURE. Protein sequencing has been the principal focus of a section of Expert's laboratory. He has led the development of technologies, protocols, and strategies needed to determine the primary structure of rare, difficult to purify proteins and peptides. High sensitivity operation and long runs are standard procedures for Expert.

PEPTIDE SYNTHESIS. Expert's lab has furnished custom synthetic peptides to many research labs and research and development facilities. He is knowledgeable of the characterization, purification, and refolding necessary for successful preparation of peptides with biological activity. His laboratory offers support to help plan the use of synthetic peptides and to select the sequence for custom syntheses and peptide use.

NUCLEIC ACIDS; RNA; DNA SEQUENCING; DNA SYNTHESIS; GENETIC ENGINEERING. Expert has directed the laboratory that has provided nucleic acid synthesis support for many applications in molecular biology, genetic engineering, biochemistry, and other fields for more than ten years. The facility has synthesized more than 10,000 oligomers and provides DNA sequencing using automated instruments to many researchers and research and development labs. Protocols are available to handle templates from diverse sources, in different vectors, single or double stranded. Mapping based on fluorescent probes to small repeats or unique sequences is performed on an automated DNA analyzer. Template purification is the primary limitation to sequencing and mapping. Maintaining working protocols is a primary focus of Expert's laboratory.

AMINO ACID SEQUENCING. Expert has sequenced proteins of diverse types using several implementations of Edman degradation for scientists around the world. Proteins or peptides purified by many different laboratories using a variety of strategies have been successfully sequenced form the amino terminus or from an internal fragmentation site.


amino acid


DNA sequencing


DNA synthesis


genetic engineering


peptide purification


peptide synthesis




protein purification


protein sequencing


protein structure


protein synthesis

Show Secondary and Basic Areas of Expertise
Expert may consult nationally and internationally, and is also local to the following cities: Los Angeles, California;  San Diego, California;  Long Beach, California;  Santa Ana, California;  Anaheim, California;  Riverside, California;  Glendale, California;  Huntington Beach, California;  San Bernardino, California;  and Chula Vista, California.

Year   Degree   Subject   Institution  
1971   Post-doctoral   Physiological Chemisty   University of Wisconsin - Madison  
1968   PhD   Genetics   University of Wisconsin - Madison  
1963   MS   Genetics   University of Wisconsin - Madison  
1962   BS   Biology   Blackburn College  

Work History:
Years   Employer   Title   Responsibilities

1998 to






Design research programs for small and startup biopharmaceutical companies, recruit CROs, negotiate and manage contracts, integrate resulting materials and data into the in house program.

1995 to 1998


University Of California, Irvine


Director, Biotechnology Resource Facility


Develop state-of-the-art capabilities in protein and DNA analysis in support of campus research programs.

1985 to 1995


University of Wisconsin Biotechnology Center


Director-Protein/DNA Sequence/synthesis Facility,


Provide suite of research resources to provide world class capabilities in protein synthesis, purification and analysis and DNA synthesis and analysis, molecular biology, hybridoma and transgenic technologies.

1971 to 1985


McArdle Laboratory for Cancer Research


Program Coordinator,


Develop and deliver high performance protein and DNA sequencing and peptide and DNA synthesis.

1971 to 1985


Department of Physiological Chemistry


Project Associate,


Develop protein sequencing capabilities in support of molecular evolution studies.

Career Accomplishments:


Professional Appointments

Executive Board, ABRF; Associate Editor, Journal of Biomolecular Techniques; Visiting Professor, Universidade de Brasília, Brazil; Visiting Professor, Facultad de Farmacia y Bioquímica, Buenos Aires, Argentina

Publications and Patents Summary

Expert has 40 publications on research topics and delivery of research resources.

Selected Publications and Publishers  
 - Journal of Biomolecular Techniques  
 - Federation of American Societies for Experimental Biology (FASEB) Journal  
 - John Wiley & Sons  
 - Biochemistry  
 - American Journal of Human Genetics  

Consulting Services:
Selected Consulting Examples:
  • Through outsourcing, I have managed research programs where only part time staff were available in house.
Recent Client Requests:
  • Expert in needed to assist in designing a small scale protein formulation lab in a CRO under cGMP.
Click the green button above to contact Expert for a free initial screening call regarding your expert consulting needs.  Expert is available for consulting to corporate, legal and government clients.  Remember, your initial screening call to speak with Expert is free.

Expert Witness:
Click the green button above to contact Expert for a free initial screening call regarding expert testimony, litigation consulting and support, forensic services, or any related expert witness services.  A few litigation needs include product liability, personal injury, economic loss, intellectual property (patent, trademark, trade secret, copyright), and insurance matters.  Remember, your initial screening call to speak with Expert is free.

Additional Skills and Services:
Supplier and Vendor Location and Selection

Expert has experience locating vendors of the following: * Synthetic DNA * Custom peptides, protein sequencing, DNA sequencing * Amino acid analysis * Mass spectrometery of biomolecules.

He has access to the following resources: * Print materials * Personal contacts.


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