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 Expert  716679

Expert in Cardiovascular Drugs & Therapy, Hypertension Development, Blood Flow, etc.


Available for your Consulting and Expert Witness Needs

Texas (TX)
USA
Education Work History Career AccomplishmentsPublicationsConsulting Services Expert Witness

Summary of Expertise:

Listed with other top experts in: 

Expert is currently studying the mechanisms which may be responsible for the development of hypertension, particularly as it relates to an increase in sodium (salt) intake. More specifically, he is primarily concerned with potential abnormalities in kidney function, which may give rise to hypertension. He has also studied, in detail, the mechanism by which drugs lower blood pressure, and examined the potential advantages of dopamine receptor agonists as antihypertensive agents. His research work in this area has contributed to the development of a compound that may soon become available for the treatment of hypertensive crisis.
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arterial hypertension

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antihypertensive drug

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hypertension

Expert has been studying the mechanisms responsible for causing certain types of acute renal failure, particularly hypovolemic shock, free radical-induced injury, and endotoxin shock. The major aim is to determine whether dopamine and/or selective dopamine receptor agonists will be effective in improving renal blood flow and function in these types of acute renal failure. Some of his studies indicate that these drugs are indeed effective in improving renal function, as well as survival in models of acute renal failure.
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cardiovascular disease

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cardiovascular system

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cardiovascular drug therapy

Dopamine, although a neurotransmitter in the brain, also serves as an important role in the periphery in controlling kidney functions by regulating renal sodium excretion. Expert's research in this area has identified receptors in the kidney where dopamine acts to increase blood flow and sodium excretion. This research has also led to the postulation that a defect in the ability of dopamine to promote sodium excretion may give rise to hypertension of renal origin. The cellular signaling mechanisms that may be responsible for such a biochemical defect are currently under investigation.
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dopamine

Expert's research in this area is aimed at determining local (biochemical and physical) humoral and nervous factors that influence blood flow to vital organs. Also, studies are conducted to determine how changes in sympathetic and neuroeffector function would modify blood flow, and the mechanism by which drug affects blood flow to selective organs, which may eventually lead to a better understanding of drug action.
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blood flow


Show Secondary and Basic Areas of Expertise
Localities:
Expert may consult nationally and internationally, and is also local to the following cities: Houston, Texas;  Pasadena, Texas;  Beaumont, Texas;  College Station, Texas;  Baytown, Texas;  Bryan, Texas;  Sugar Land, Texas;  Port Arthur, Texas;  Galveston, Texas;  and Missouri City, Texas.

Education:
Year   Degree   Subject   Institution  
1975   Ph.D.   Pharmacology   University of Houston  
1968   M.S.   Pharmacology   Columbia University  
1966   B.S.   Pharmacy   Gujarat University - India  

Work History:
Years   Employer   Department   Title  

1991 to 2002

 

University of Houston

 

College of Pharmacy

 

Dean and Professor

 

1989 to 1991

 

University of Houston

 

College of Pharmacy

 

Professor and Chairman

 

1988 to 1989

 

University of Houston

 

College of Pharmacy

 

Associate Professor and Chairman

 

1975 to 1980

 

University of Houston

 

College of Pharmacy

 

Assistant Professor

 

Career Accomplishments:
Associations/Societies

Expert is a member of 16 scientific and professional societies and serves on several committees of various associations.

Professional Appointments

He serves as Editor-in-Chief for the journal Clinical and Experimental Hypertension, and he is a member of the editorial boards of Experimental Biology and Medicine and of Hypertension Research.

Awards/Recognition

Expert received the Research Excellence Award from Sigma Xi, the scientific research society. He is a Fellow of the Council for High Blood Pressure Research of the American Heart Association.


Publications:
Publications and Patents Summary

He is Associate Editor of five books, co-editor of two journal supplements, has written 23 book chapters, 19 review articles, and 120 research papers in scientific journals.

Selected Publications and Publishers  
 - European Journal of Pharmacology, Molecular Pharmacology  
 - Naunyn-Schmiedeberg's Arch. Pharmacol.  
 - European Journal of Pharmacology  

Consulting Services:
Click the green button above to contact Expert for a free initial screening call regarding your expert consulting needs.  Expert is available for consulting to corporate, legal and government clients.  Remember, your initial screening call to speak with Expert is free.

Expert Witness:
Click the green button above to contact Expert for a free initial screening call regarding expert testimony, litigation consulting and support, forensic services, or any related expert witness services.  A few litigation needs include product liability, personal injury, economic loss, intellectual property (patent, trademark, trade secret, copyright), and insurance matters.  Remember, your initial screening call to speak with Expert is free.

Additional Skills and Services:
Training/Seminars

Expert has been invited to 42 international conferences and has presented 38 seminars to academic groups and pharmaceutical industries.


 

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