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 Expert  722043

Expert in Clinical Chemistry, Laboratory Diagnostics, Immunoassay Development, Therapeutic Drug Monitoring

Available for your Consulting and Expert Witness Needs

New York (NY)
Education Work History Career AccomplishmentsPublicationsConsulting Services Expert Witness

Summary of Expertise:

Listed with other top experts in: 

Expert has extensive experience in the field of clinical chemistry and clinical diagnostics. Development of analytical methods for trace analytes in biological fluids, especially in the field of clinical diagnostics, has been Expert's main job responsibility and success over the last 15 years. While his primary experience and major contributions lie in the area of developing immunoassay methods, many other biochemical techniques had to be mastered in completing his projects. Protein biochemistry, immunochemistry, electrophoresis, various kinds of purification and chromatographic techniques, organic synthesis, protein purification and conjugation, and determination of purity of biomolecules are all topics he is well-versed in.

Expert has synthesized several dye polymers, conjugated them to analytes like thyroxine, to develop a thyroxine immunoassay. He has so far developed homogeneous or heterogeneous immunoassays, using colorimetric, enzyme, or chemiluminescent labels, and many types of paramagnetic, or otherwise 'beads' for some twenty analytes in clinical diagnostics, including drugs that need therapeutic monitoring. He has many publications in the field and is frequently invited to give seminars in national and international conferences.

Expert has developed commercially sold methods for therapeutic drug monitoring of several cardioactive, antiasthmatic, antiepileptic and antibiotic drugs. He has written some 20 papers, presented more than 30 posters, and given seminars in many national and international conferences on therapeutic drug monitoring in human, drug toxicology and drug-drug interaction.


analysis technique




clinical diagnostics




protein biochemistry


clinical chemistry




assay development


drug blood level determination


drug toxicology


drug-drug interaction


drug monitoring


therapeutic drug monitoring

Show Secondary and Basic Areas of Expertise
Expert may consult nationally and internationally, and is also local to the following cities: Philadelphia, Pennsylvania;  Allentown, Pennsylvania;  Reading, Pennsylvania;  Bethlehem, Pennsylvania;  Lancaster, Pennsylvania;  Trenton, New Jersey;  Camden, New Jersey;  Wilmington, Delaware;  Baltimore, Maryland;  and Alexandria, Virginia.

Year   Degree   Subject   Institution   Honors
1983   Ph.D.   Bio-Organic Chemistry   Yale University   Highest GPA
1978   M.Phil.   Biochemistry   Yale University   4.0 GPA
1977   M.S.   Biochemistry   Yale University   4.0 GPA
1975   M.S.   Organic Chemistry   Indian Institute of Technology   4.0 GPA
1973   B.S.   Chemistry   Calcutta University   4.0 GPA

Work History:
Years   Employer   Department   Title   Responsibilities

1992 to




Chiron Diagnostics


Manager, Assay Development


Expert is manager of Chiron's assay development for their automated chemiluminescent immunoassay systems.

1989 to 1992


Cirrus Diagnostics



Senior Scientist


Expert was engaged in the development of and regulatory filing for immunoassays for the automated IMMULITE analyzer.

1984 to 1989


Photest Diagnostics





He researched the synthesis and conjugation of chromogenic polymers to biomolecules, and also worked on immunoassay development.

1983 to 1984


University of Texas


Department of Pathology


Postdoctoral Fellow


Expert's postdoc work at the Univ. of Texas consisted of research in clinical diagnostics. Additionally, he acted as Assistant Director of Clinical Chemistry.

Career Accomplishments:

Expert is a member of the American Association of Clinical Chemistry (AACC), the International Federation of Clinical Chemistry, the International Association of Therapeutic Drug Monitoring, and the Clinical Ligand Assay Society (CLAS).


He has the distinction of receiving the highest certification in clinical chemistry – Expert is a certified Diplomate from the American Board of Clinical Chemistry (ABCC) in Washington, D.C.

Professional Appointments

He is on the Editorial Board for the AACC's bimonthly Therapeutic Drug Monitoring (Ther Drug Monit), and is an Edit Reviewer for Life Sciences, the Journal of Immunochem. Research, and AACC National Meeting Abstracts.


Expert has received numerous awards and merits for his work. He won Best Speaker Award at the AACC National Meeting, San Francisco, 2000 and the Clinical Chemistry Recognition Award from the association in April 1999. He was the recipient of a Quality Recognition Award from Chiron Diagnostics in 1996. During his graduate studies at Yale University, Expert obtained the highest GPA (4.0 equivalent) and a Merit Fellowship from the school. Prior to this, he was National Science Talent Scholar, Government of India, 1969-75, and National Scholar, Government of India (based on 1969 top scorer in National Merit Test, Government of India).

Publications and Patents Summary

He has 38 papers, 46 abstracts, and four patents in the field of analytical chemistry, clinical chemistry, immunoassay development, and therapeutic drug monitoring-clinical toxicology.

Selected Publications and Publishers  
 - American Journal of Clinical Pathology  
 - Clinical Chemistry  
 - Clinical Biochemistry  

Consulting Services:
Selected Consulting Examples:
  • Expert was a consultant to Chiron Diagnostic's deoxypyridinoline assay development, when the team faced serious technical issues. He developed methods and assisted the team to investigate why the new assay sometimes gave incorrect clinical results, and showed how it could be fixed.
  • He was asked to consult and assist in Chiron's ACS:180® (Automated Chemiluminescence System) vancomycine assay product. He developed a new way to conjugate the chemiluminescent label to the analyte. The new process reduced process time by 60% and cost by 78%, and made the process more reliable.
Recent Client Requests:
  • Expert in Immunoassay constultants for consulting on Immuoassay Development.
  • Immunoassay expert for consulting on substrates market.
Click the green button above to contact Expert for a free initial screening call regarding your expert consulting needs.  Expert is available for consulting to corporate, legal and government clients.  Remember, your initial screening call to speak with Expert is free.

Expert Witness:
Recent Litigation Client Requests:
  • Expert analytical chemist for consulting on evaluation of prosecutorial claims that an enzymatic assay to test for ETOH is equivalent to a whole blood test done on gas chromotography.
  • Expert in chemistry for consulting on Abbott Aeroset, Celldyne 3700 and Axsym analyzers.
Click the green button above to contact Expert for a free initial screening call regarding expert testimony, litigation consulting and support, forensic services, or any related expert witness services.  A few litigation needs include product liability, personal injury, economic loss, intellectual property (patent, trademark, trade secret, copyright), and insurance matters.  Remember, your initial screening call to speak with Expert is free.

Language Skills:
Foreign Language   Description
German   Expert reads and writes German well. The language was a graduate school requirement, used in perusing scientific literature.
Hindi   He learned Hindi in school in India.
Bengali   Expert is highly proficient in Bengali, his mother tongue.

Additional Skills and Services:

Expert has delivered many presentations during his professional career. He presented a workshop on assay interference at the National Meetings of the American Association of Clinical Chemistry in 1998 and 2000. He also presented roundtables on various topics in clinical diagnostics at: the National Meetings of the AACC, 1995-2000, the International Federation of Clinical Chemistry in Florence, Italy, 1999, the International Congress of Clinical Chemistry in London, 1996, and the International Conference of Therapeutic Drug Monitoring in Vienna, 1995.

Supplier and Vendor Location and Selection

He has much experience with HPLC, having set up high performance liquid chromatography systems at his employers. This involved screening and choosing a vendor, arranging set-up and supervising instrument use.


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