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 Expert  725879

Expert in Biotechnology, Enzymes, Environmental Bioremediation, Regulatory Compliance


Available for your Consulting and Expert Witness Needs

Illinois (IL)
USA
Education Work History Career AccomplishmentsPublicationsConsulting Services Expert Witness

Summary of Expertise: Listed with other top experts in: 
Expert has over 40 years of experience in both basic and applied Biochemistry (biochemical research and enzymology) and Biotechnology. He is very successful in finding flaws in published and spoken materials. His strengths are in the fields of physical biochemistry, protein biochemistry, protein characterization, protein modification, protein stabilization and protein structure. He is familiar with many chromatography applications, as he has employed adsorption chromatography, as well as ion exchange and gel permeation chromatography (column and TLC) for small molecule and protein isolation, enzyme purification, and protein purification. A protein concentration process, usually via membranes and pressure filtration, followed the purifications. Some enzymes that he purified and studied were hemoglobin, methemoglobin, methemoglobin reductase, superoxide dismutase, glutathione peroxidase, glucose isomerase, glucoamylase, and numerous other enzymes such as lipases, esterases (especially pig liver esterase), proteases, hydrolases, oxidative enzymes, and oxidoreductases, and other proteins such as immunoglobulins. He is very familiar with HPLC (high-performance liquid chromatography) and associated detectors. He is very strong in analytical biochemistry and has experience in managing an analytical biochemistry laboratory where such techniques as UV/Vis spectrophotometry, GC/MS, ion chromatography and the like were in common quantitative and forensic usage. He studied free radical biochemistry and showed its negative effects on various blood proteins and related it to peroxidase (HRP). He has had success in applied and industrial enzymology (biochemical process development), especially with immobilized enzymes.

Expert has over 23 years' experience in the environmental, wastewater and air treatment areas, focusing on biological approaches. He has been an expert witness on approximately seven cases and has yet to be on the losing side. He is familiar with many areas of wastewater treatment, focusing on industrial and hazardous wastewater treatment. Examples of experience include, but are not limited to, biological industrial wastewater treatment such as the biological treatment of Manufactured Gas Plant (MGP)-impacted (contaminated) groundwater, fixed film reactors for reduction of biochemical oxygen demand (BOD) and COD, drinking water organics control using both biological treatment and activated carbon adsorption, anaerobic industrial wastewater digestion, both for sludge reduction and for co-metabolic treatment of halogenated hydrocarbons such as TCE, and nitrated compounds such as TNT and DNT (pink water), drinking water purification, especially nitrification – denitrification and BOD reductions as applied to the Space Station water recycling, in-situ groundwater treatment (toxic substance contaminated water treatment) using biological systems, and wastewater recycling, especially for the semi-conductor industry. He has significant experience in Asia (China, Taiwan, and Singapore) in the environmental area.

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biochemical research

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biochemistry

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chromatography

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cytochrome

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enzyme

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enzyme purification

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enzymology

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free radical biochemistry

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gel permeation chromatography

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hemoglobin

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high-performance liquid chromatography detector

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protein biochemistry

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protein characterization

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protein concentration process

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protein isolation

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protein modification

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protein purification

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protein stabilization

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protein structure

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biochemical process development

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esterase

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immobilized enzyme

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anaerobic industrial wastewater digestion

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biochemical oxygen demand

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biological industrial wastewater treatment

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groundwater treatment

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industrial wastewater treatment

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toxic substance contaminated water treatment

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wastewater treatment

Expert has over 18 years experience in the regulatory field, focusing on such areas as chemical process safety engineering. He has been very successful in representing clients involved in alleged violation of OSHA and EPA regulations. He has worked with numerous clients to achieve compliance with various regulations, including EPA 112r (Risk Management Planning, RMP), TSCA regulations, especially involving PCBs, SARA Title III, EPCRA, Occupational Safety and Health Administration (OSHA) regulations [especially 29 CFR 1910.119, Process Safety Management (PSM) and other areas such as OSHA 29 CFR 1910.146 and OSHA 29 CFR 1910.1030, confined space safety, etc]. He also has significant experience in food safety, especially HACCP and Sanitation SOPs. Much of his work has involved the food and beverage areas, especially involving ammonia refrigeration, and the chemical areas.
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chemical process safety management

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chemical process safety engineering

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Occupational Safety and Health Administration

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process safety management


Show Secondary and Basic Areas of Expertise
Localities:
Expert may consult nationally and internationally, and is also local to the following cities: Chicago, Illinois;  Rockford, Illinois;  Aurora, Illinois;  Naperville, Illinois;  Joliet, Illinois;  Elgin, Illinois;  South Bend, Indiana;  Gary, Indiana;  Milwaukee, Wisconsin;  and Madison, Wisconsin.

Often requested
with this expert:

Water Treatment
Environmental Consulting - Industrial Wastewater & Process...
Water and Wastewater Treatment, Nanofiber and Nanotube...
Influent, Boiler, Cooling and Waste Treatment, Refinery,...

Education:
Year   Degree   Subject   Institution   Honors
1978   Post Doctoral Scholar   Biochemistry   Cornell University  
1976   PhD   Biological Chemistry   The University of Michigan  
1971   BA   Chemistry   Queens College, CUNY   Honors

Work History:
Years   Employer   Department   Title   Responsibilities

1999 to

 

(Undisclosed)

 


 

President and Member

 

He is currently a senior consultant, president and founder. His focus is on (1) biotechnology using immobilized enzymes to produce pharmaceutical intermediates, (2) Immobilized cells for industrial wastewater treatment and (3) Regulatory (OSHA, EPA) compliance

1995 to 1999

 

Sole Proprietorship

 


 

Self

 

His focus was on (1) biotechnology using immobilized enzymes to produce pharmaceutical intermediates, (2) Immobilized microorganisms for industrial wastewater treatment and (3) Regulatory (OSHA, EPA, DHS, DOT, USDA) compliance

1996 to 1997

 

Honeywell International (fka AlliedSignal)

 

Aerospace/Biotechnology

 

Project leader

 

He was project leader involving the use of immobilized microorganisms for total water recycle for the Mars Lander/Space Station

1994 to 1995

 

AlliedSignal

 

Environmental Systems and Services

 

Manager

 

He applied the use of immobilized cells for the biological treatment of hazardous waste and aided in the commercialization as co-founder of the Environmental Systems and Services business unit.

1985 to 1994

 

AlliedSignal Research & Technology

 


 

Research Scientist

 

In this capacity he invented and patented a number of new technologies and materials for wastewater and groundwater pretreatment (received Special Award) based upon immobilized cell technology.

1982 to 1985

 

Signal-UOP Research Center

 

Biochemistry

 

Research Specialist

 

During this period of time his area of work was quite diverse, involving biochemistry, the corn wet milling area, immobilized enzymes, anti-microbial pharmaceuticals, coating technology and electro-biochemistry.

1978 to 1982

 

UOP Research Center

 

Biotechnology Department

 

Senior Research Biochemist

 

In this position his work focused on the industrial application of immobilized enzymes used in continuous processes.


Career Accomplishments:
Associations/Societies

American Chemical Society

Licenses/Certifications

He has special training: · HAZWOPPER Refresher Training (8 hour Haz. Waste Operations Management), 1991 to Current (2008). · Emergency Notification Release Reporting Training, EPCRA 304; CERCLA 103 (EPA Region 5), 1999 · Risk Management Program Assistance (IEMA), 1999 · Basic Ammonia Refrigeration, 1998 · Statistical Design of Experiments (DOE), 1996. · Scorecard Training, 1996. · Convenor, Pollution Prevention Biotechnology, Summer Biotechnology Institute, Northwestern University Center for Biotechnology, 1995. · Sales Training Workshop (Institute for Business and Interpersonal Strategies) 1995. · Customer Linked Commercialization & Customer Partnering, 1994.

Professional Appointments

He was appointed Trustee, Plum Grove Estates Sanitary District, by Cook County, Illinois, and is currently serving in his ninth year.

Awards/Recognition

Expert has received a number of awards and recognition, including: • Special (Team) Recognition Award, AlliedSignal, April, ‘95. • Special (Individual) Recognition Award, AlliedSignal, May, ‘92. • Rackham Dissertation Grant, The University of Michigan, ‘74-‘75. • Graduated (BA, Queens College) with departmentally-conferred honors, ‘71. • Elected to Beta Delta Chi, Chemistry Honor Society, Queens College, CUNY, ‘71. • New York State Regents Scholarship, ‘67-‘71.

Medical/Professional Internships

Honors research, in the laboratory of Prof. Robert Engel, Queens College, CUNY, January 1970 through August 1971


Publications:
Publications and Patents Summary

Expert has authored approximately 22 publications, 3 book chapters, and is an inventor on 13 issued patents, 3 pending patents, in biotechnology, including the chemical, food, pharmaceutical, industries, and for biological wastewater treatment.

Selected Publications and Publishers  
 - Engineering in Life Sciences  
 - John Wiley and Sons  
 - U.S. Patent and Trademark Office  
 - Archives of Biochemistry and Biophysics  
 - Journal of Medicinal Chemistry  

Government Experience:
Years   Agency   Role   Description
2004 to 2008   Dept. of Agriculture   Consultant   Consulted on USDA-invented process via ISoy Technologies, for enzymatic production of soybean oil ferulated esters.

Consulting Services:
Selected Consulting Examples:
  • He is currently aiding ISoy Technologies, a small start-up firm, producing ferulated soybean oil glycerides in a reaction catalyzed by immobilized CalB [Candida antarctica lipase B]. The original technology was developed at the USDA Labs in Peoria, IL. ISoy is in the early production stage for this semi-synthetic hydrophobic additive used topically as both a sunscreen and an antioxidant.
  • He successfully completed his biotechnology project for Gilead Sciences Inc. to produce immobilized pig liver esterase, ImPLE in commercial quantities. The regio- and stereospecificity of the ImPLE was essential for the production of Coviracil (Emtricitabine, FTC, Emtriva), the newer once-a-day nucleoside reverse transcriptase inhibitor HIV/AIDS drug.
  • He worked with scientists at Thermogen, Medichem and DeCode Genetics to develop a microbiological process for the synthesis of natural and unnatural amino acids based upon the use of hydantoinase and related enzymes.
Recent Client Requests:
  • Expert in waste water.
  • Expert in Industrial Water Treatment Forum.
  • Expert in Cost Modeling for Pesticide Encapsulation.
  • Solid filtration expert for consulting on Sea Water Filtration.
  • Expert in Protein Biochemistry
Click the green button above to contact Expert for a free initial screening call regarding your expert consulting needs.  Expert is available for consulting to corporate, legal and government clients.  Remember, your initial screening call to speak with Expert is free.

Expert Witness:
Expert Witness Experience Summary:
- Gave deposition, at request of MWRDGC attorneys (plaintiff), relating to allegation that company AY (defendant, an ex-client) was inappropriately discharging high-strength wastewater. - In another case, collected data for defendant and wrote report outlining how alleged groundwater contamination at plaintiff residence was below state drinking water regulations. - Gave deposition on same. - Opposing attorney of above case (plaintiff) settled out of court due to strength of data, report and deposition. - In another case, consulted for plaintiff in patent infringement case relating to the use of microorganisms to aid in the degreasing of machine parts. - In another case, gave deposition on behalf of plaintiff on alleged groundwater contamination of drinking water with benzene and other petroleum components. Also performed calculations based upon EPA data on degree of effectiveness for activated carbon to remove the above contaminants. Trial currently pending.
Recent Litigation Client Requests:
  • Expert in anhydrous ammonia fertilizer safety for toxic tort litigation case.
  • Expert for consulting on Roeder case.
  • Expert in amonia fertilizer for wrongful death litigation.
Click the green button above to contact Expert for a free initial screening call regarding expert testimony, litigation consulting and support, forensic services, or any related expert witness services.  A few litigation needs include product liability, personal injury, economic loss, intellectual property (patent, trademark, trade secret, copyright), and insurance matters.  Remember, your initial screening call to speak with Expert is free.

International Experience:
Years   Country / Region   Summary
2006 to 2008   China (PRC)   He went to China (PRC), Taiwan (ROC) and Singapore on a series of major consulting assignments for Honeywell. During these trips he made presentations to current and prospective customers for the wastewater and air treatment technologies that he had invented and patented while a Honeywell employee. He performed troubleshooting duties with problems that involved difficult-to-treat wastewater, both on-site and off-site. For example, he spent Christmas 2007 at the Hangzhou Transfar Whyyon Chemical Co site (a couple of hours from Shanghai, China) starting up the full-scale Biological Air Treater he had invented and patented. It is based upon a microbial fixed-film (immobilized) consortium and acts to irreversibly mineralize vaporous pollutants at the plant.
1996 to 2000   Taiwan (ROC)   He aided CPC (Chinese Petroleum Company), Taiwan (ROC), in evaluating fixed film (biological) reactor technology for the treatment of toxic, difficult refinery waste streams, mostly derived from residual oil cracking.
1995 to 1995   Taiwan (ROC)   He went to Taiwan to aid in developing a method of leaching or fixing heavy metals contaminating a major river in southern Taiwan.

Additional Skills and Services:
Training/Seminars

Presented as Invited Speaker, to Environmental Practice Specialty, American Society of Safety Engineers ASSE Headquarters, 1800 Oakton, Des Plaines, IL, USA. “Thoughts on International Trends (China) and Emerging Water Issues” April 13, 2007

Supplier and Vendor Location and Selection

In order to complete a high priority project for a major pharmaceutical firm, he procured, installed and validated a bioanalytical laboratory in six weeks.


 

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