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 Expert  727550

Expert in Genomic Technologies, Bioinformatics, Computational Biology and their Applications


Available for your Consulting and Expert Witness Needs

Massachusetts (MA)
USA
Education Work History Consulting Services Expert Witness Market Research

Summary of Expertise:

Listed with other top experts in: 

Expert completed is PhD in theoretical physics and two years as a postdoctoral fellow in physics before receiving a five-year fellowship to work on the Human Genome Project. He began working on genome mapping at the Salk Institute in 1992, focusing on creating a physical map of human chromosome 11. In 1994, he moved to the Stanford Human Genome Center at Stanford University, where his work focused on developing new strategies for sequencing regions of human chromosome 21 associated with Down's Syndrome and regions of chromosome 2 associated with Huntington's Disease. in 1997, he was recruited to the faculty at The Institute for Genomic Research (TIGR) in Rockviille, MD, where he was a pioneer in the development and application of DNA microarray technologies and the creation of software tools and databases for its analysis. While at TIGR, he established himself as a world leader in genomics and functional genomics and the emerging fields of bioinformatics and computational biology. In 2005, he joined the faculty at the Expert's Firm and Expert's Firm where his work focused on genomic profiling using DNA arrays and Next-Generation DNA sequencing technologies to the study of human disease with a focus on women's cancers.

His work has led to more than 150 publication is high-profile peer-reviewed journals, numerous book chapters, tutorials, and editorials. He serves as editor-in-chief for the journal Genomics and on the editorial boards of numerous other scientific journals focused on genomics and bioinformatics. He is in high demand as a speaker and has given a number of prestigious national and international lectures.

He and his group have developed many of laboratory protocols that are in wide use for genomic analysis. The software tools he has created for the analysis of genomic data have been downloaded well over 50,000 times and he estimates more than 100,000 users world-wide. He had been a leader in the development of standards for data sharing and in the open-source software movement. He has served on numerous grant review panels in the US and Europe and has served on four National Resource Council panels focused on data sharing and applications of genomics.

Expert is also on numerous scientific advisory boards, including serving on the boards of St. Jude's Children's Research Hospital, the Lovelace Respiratory Institute, and the EPA's Board of Scientific Counselors.

Expert is also a gifted teacher and communicator and recently completed a book focused on explaining the sequencing of the human genome and its applications to a broad audience.

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amino acid sequence

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analysis

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bioinformatics

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biological engineering

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biotechnology

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chromosome

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chromosome paint

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clinical genetics

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DNA

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DNA manipulation

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DNA sequencing

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DNA technology

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eukaryotic gene

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gene

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gene characterization

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gene expression

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gene fusion

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GeneScan

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genetic disease

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genetic engineering

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genetic manipulation

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genetic mutation process

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genetic sequencing

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genetics

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genome

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genomics

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genotype

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Genotyper

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genotyping

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genotyping software

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human genome

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medical genetics

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molecular biology

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mutagenesis

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nucleotide mapping

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pharmacogenomics

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plasmid DNA

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protein

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protein analysis

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proteome

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proteomics

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recombinant DNA

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recombinant DNA technology

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restriction endonuclease

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RNA sequencing

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structural bioinformatics

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transgenic animal

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transgenic technology

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computational biology


Show Secondary and Basic Areas of Expertise
Localities:
Expert may consult nationally and internationally, and is also local to the following cities: Boston, Massachusetts;  Worcester, Massachusetts;  Springfield, Massachusetts;  Lowell, Massachusetts;  Cambridge, Massachusetts;  Brockton, Massachusetts;  Hartford, Connecticut;  Waterbury, Connecticut;  Manchester, New Hampshire;  and Providence, Rhode Island.

Education:
Year   Degree   Subject   Institution  
1990   PhD   Quantum Field Theory and String Theory Models   UCLA Department of Physics  
1984   MS   Theoretical Particle Physics   UCLA Department of Physics  
1983   BS   Physics   California Institute of Technology  

Work History:
Years   Employer   Department   Title   Responsibilities

2005 to

 

(Undisclosed)

 

Biostatistics

 

Professor of Bioinformatics and Computational Biology

 

Expert's position involves course development, teaching, and supervising graduate students and postdoctoral fellows in their research.

2005 to

 

Expert's Firm

 

Dept. of Biostatistics and Computational Biology and Dept. of Cancer Biology

 

Professor

 

Expert's work focuses on information integration approaches to the analysis of genomic data and its application to the study of human disease with a focus on women's cancers. His work involves both laboratory and computational approaches and includes the application of DNA microarray technologies and Next-Generation DNA sequencing.

He also directs the Center for Cancer Computational Biology, a consulting service that supports genomic data analysis for a large number of academic and commercial organizations.

1997 to 2005

 

The Institute for Genomic Research

 

Dept. of Mammalian Genomics and Dept of Bioinformatics

 

Investigator

 

Expert's work focused on the development of DNA microarray technology, bioinformatics applications to support functional genomics, and their applications to a wide range of questions ranging from drought resistance in human cancer to drought resistance in plants. Expert also worked extensively in the analysis of whole genome sequence data and gene prediction and annotation.

1994 to 1997

 

Stanford University

 

Stanford Human Genome Center

 

Staff Scientist

 

Expert was responsible for developing new approaches to the sequencing of the human genome, with application to human chromosomes 21 and 4; this work included the development of both laboratory protocols and software systems and databases for data analysis. Expert also worked extensively on the development of radiation hybrid maps of the human genome.

1992 to 1994

 

The Salk Institute

 

Molecular Genetics Laboratory

 

Research Scientist

 

Expert was responsible for developing laboratory and computational strategies that led to the physical mapping of human chromosome 11.


Consulting Services:
Click the green button above to contact Expert for a free initial screening call regarding your expert consulting needs.  Expert is available for consulting to corporate, legal and government clients.  Remember, your initial screening call to speak with Expert is free.

Expert Witness:
Expert Witness Experience Summary:
He has served as an expert witness in three intellectual property cases revolving around intellectual property associated with DNA arrays and DNA sequencing technologies. This involved preparation of expert reports, testifying in Markman hearings, giving depositions, and testifying in trial, all in federal district courts.

He also served as an expert in a biotech criminal case that involved the alleged theft of IP by a former employee.

Click the green button above to contact Expert for a free initial screening call regarding expert testimony, litigation consulting and support, forensic services, or any related expert witness services.  A few litigation needs include product liability, personal injury, economic loss, intellectual property (patent, trademark, trade secret, copyright), and insurance matters.  Remember, your initial screening call to speak with Expert is free.

Market Research:
He is on the scientific advisory boards of a number of sequencing technology companies and is an expert on genomic technologies for GLG Councils, where he is asked for his opinion on DNA technologies between two and four times each month.

Click the green button above to contact Expert for a free initial screening call regarding your marketing research, industry research, and company research needs.  For research needs involving multiple experts or secondary research, a Research Director can be assigned to coordinate the work into a custom report for you as a potentially quicker and more cost effective alternative to doing this work yourself or hiring a boutique consultancy.  Remember, your initial screening call to speak with Expert is free.

Additional Skills and Services:
Training/Seminars

He has developed and presented countless seminars, workshops, short courses, and full courses throughout his career. He has also given numerous talks to public and civic groups and schools on genomics and its applications. He recently completed a book on genomics and its applications aimed at a mass-market audience that is scheduled for publication in spring of 2010.

Supplier and Vendor Location and Selection

He has done quite a bit of work finding vendors and suppliers for technologies ranging from laboratory instruments, genome sequencing and microarray technologies, and high-performance computing hardware and software.

Other Skills and Services

He has been involved in almost every aspect of biotechnology ranging from laboratory technologies to software for data analysis and applications to a wide range of topics including personalized medicine.


 

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