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 Expert  728553

Expert in Drug Discovery, Neuropharmacology, Serotonin, Dopamine, Antipsychotics, Pharma Project Management

Available for your Consulting and Expert Witness Needs

Education Work HistoryPublicationsConsulting Services Expert Witness Market Research

Summary of Expertise:

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Expert is an industrial neuropharmacologist with seventeen years of proven achievement in preclinical drug discovery of novel antipsychotics, antidepressants and analgesics (examples of drugs characterised: milnacipran, befiradol, F15599, F15063). He has significant expertise in serotonin receptor pharmacology, defining target selection and validation criteria, project management, building experimental flow charts, and candidate profiling. He has extensive management experience of multidisciplinary pharmacology research. He has demonstrated proven leadership of project teams including medicinal chemists, early ADMET and preclinical development partners. Collaborations with academic researchers. Participation in Due Diligence and licensing exchanges.

Expert has written numerous publications (>120) in peer-reviewed journals and multiple symposia presentations. He speaks three languages: English, French, and Italian.

His therapeutic areas of interest include schizophrenia, depression, anxiety / stress, chronic / neuropathic pain and Parkinson's disease.

Molecular targets characterised: monoamine receptors and transporters, with emphasis on serotonin 5 HT1A and 5-HT2 receptors, dopamine D2, D3 and D4 receptors and alpha2 adrenergic receptors. Additional targets investigated: glutamate NMDA receptors and sodium channels.






central nervous system




drug screening










pharmaceutical industry







Show Secondary and Basic Areas of Expertise

Year   Degree   Subject   Institution   Honors
1992   PhD   Neuropharmacology   University of Kent at Canterbury  
1988   BSc   Biochemistry   University of Kent at Canterbury   Honors (2-1)

Work History:
Years   Employer   Department   Title   Responsibilities

2010 to







Expert provides strategic consulting in pre-clinical neuropharmacology and drug discovery. Clients are principally biotech and pharmaceutical companies seeking an independent expert opinion on project management, flow-chart and team organisation and drug profiling. Specialty areas: serotonergic mechanisms and antipsychotics.

2002 to 2010


Pierre Fabre Laboratories


Neurobiology 2 Division




Responsibility for discovery and pharmacological characterisation of novel molecules aimed at treatment of psychiatric disorders (including schizophrenia, depression) and chronic pain. Novel molecules were put into development (F15063: putative antipsychotic; F15599: potential antidepressant / analgesic). Principal therapeutic targets: serotonin 5-HT1A and 5-HT2B, dopamine D2, D3 and D4 receptors. Highly interactive position requiring excellent communication skills, responsibility for staff recruitment and training, progress reports to higher management, participation in drug development teams and preparation of “Due Diligence” dossiers for presentation to potential licensing partners. Direct scientific and administrative management of a multidisciplinary division comprising ~20 FTEs, including 5 Ph.D. scientists. “Dotted-line” management of a further dozen pharmacologists in other departments

1993 to 2002


Servier Research Institute


Psychopharmacology Division


Laboratory Head


Management of an in vitro pharmacology group consisting of 5 FTEs including a Ph.D. scientist with responsibility for drug screening programme on >20 receptor subtypes and re-uptake sites. Mechanistic investigation of molecular pharmacology of monoamine receptors, including G-protein and MAP kinase activation profiles of dopamine and serotonin receptors.

Publications and Patents Summary

Peer-reviewed publications in international journals : over 120, mainly in neuropharmacology journals. Principal areas: serotonin and monoamin pharmacology, antipsychotics, intracellular signal transduction, antidepressants, pain. Abstracts and conference lectures : over 160. Patents : 8 published, 1 filed.

Selected Publications and Publishers  
 - International Journal of Neuropsychopharmacology  
 - British Journal of Pharmacology  
 - European Journal of Pharmacology  
 - Current Opinion in Investigational Drugs  
 - Neuropsychopharmacology  

Consulting Services:
Click the green button above to contact Expert for a free initial screening call regarding your expert consulting needs.  Expert is available for consulting to corporate, legal and government clients.  Remember, your initial screening call to speak with Expert is free.

Expert Witness:
Click the green button above to contact Expert for a free initial screening call regarding expert testimony, litigation consulting and support, forensic services, or any related expert witness services.  A few litigation needs include product liability, personal injury, economic loss, intellectual property (patent, trademark, trade secret, copyright), and insurance matters.  Remember, your initial screening call to speak with Expert is free.

Language Skills:
Foreign Language   Description
French   Fully fluent
Italian   Intermediate level

Market Research:
Extensive knowledge of drug discovery process from medicinal chemistry to preclinical development. Expert drug hunter with particular focus on close association of mechanistic innovation ("first in class" drugs) with realistic development criteria. Broad team management and project design experience.

Click the green button above to contact Expert for a free initial screening call regarding your marketing research, industry research, and company research needs.  For research needs involving multiple experts or secondary research, a Research Director can be assigned to coordinate the work into a custom report for you as a potentially quicker and more cost effective alternative to doing this work yourself or hiring a boutique consultancy.  Remember, your initial screening call to speak with Expert is free.

Additional Skills and Services:
Other Skills and Services

Specialty expertise in serotonin pharmaology and antipsychotics. Widely recognised scientist in pharmaceutical industry (cf. publication record)


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